Phage Characterization:

  • Phage susceptibility on clinical isolates
  • Phage Genome Sequencing and annotation
  • Bacteria Genome Sequencing and annotation
  • Bioinformatic analysis of potential toxins, and deleterious elements
  • Transmission electron microscopy (TEM)
  • Generalized transduction assays
  • Determination of infection cycle parameters such as phage adsorption rate, latent period, and burst size
  • Emergence frequency of bacteriophage insensitive mutants
  • ICH phage stability
  • Selection of production non-pathogenic host